Discontinuation of low-dose aspirin reverses its prophylactic effect
نویسندگان
چکیده
منابع مشابه
Prophylactic Low-Dose Aspirin Therapy
Background. The influence of prophylactic low-dose aspirin on the clinical characteristics of subsequent nonfatal myocardial infarction was examined in the Physicians' Health Study, a randomized, double-blind placebo-controlled trial of alternate-day aspirin (325 mg) among 22,071 US male physicians. Methods and Results. During 60.2 months of follow-up, 342 incident cases of nonfatal myocardial ...
متن کاملLow-Dose Aspirin Discontinuation and Risk of Cardiovascular Events: A Swedish Nationwide, Population-Based Cohort Study.
BACKGROUND There are increasing concerns about risks associated with aspirin discontinuation in the absence of major surgery or bleeding. We investigated whether long-term low-dose aspirin discontinuation and treatment gaps increase the risk of cardiovascular events. METHODS We performed a cohort study of 601 527 users of low-dose aspirin for primary or secondary prevention in the Swedish pre...
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OBJECTIVE To evaluate the effect of maternal low dose aspirin ingestion in platelet function of newborn. DESIGN Prospective randomized placebo controlled study. METHODS 25 neonates born to mothers receiving low dose aspirin and 25 matched neonates with no maternal exposure to aspirin were studied. 2 ml of EDTA and 4.5 ml of citrate blood was collected from umbilical vein using double clampe...
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UNLABELLED Antiplatelet agents are pivotal for prevention of coronary artery disease and cerebrovascular disease worldwide. Individual patient data meta-analysis indicates that low-dose aspirin causes a 10% risk reduction in pre-eclampsia for women at high individual risk. However, in the last 15 years it has emerged that a significant proportion of aspirin-treated individuals exhibit suboptima...
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graphic deterioration, in the patient and others affected by aerosols of contaminated water in other factories2 3 no radiographic changes were evident after several years' exposure, and no functional abnormalities persisted when away from work. Furthermore, the symptoms were prominent in the early part of the week, improving while continuing at work, but recurring on return to work after an abs...
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ژورنال
عنوان ژورنال: Nature Reviews Cardiology
سال: 2011
ISSN: 1759-5002,1759-5010
DOI: 10.1038/nrcardio.2011.123